ROR1 |
ROR-gamma-t(+) FoxP3(+) biTregs |
chain fibers |
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[receptor tyrosine kinase-like orphan receptor 2; RTK-like orphan receptor 2] also: NTRKR2 [Neurotrophic tyrosine kinase receptor-related 2] (Masiakowski and Carroll, 1992). The ROR2 cell surface receptor tyrosine kinase has been identified as a member of the neurotrophic trk gene family (Masiakowski and Carroll, 1992). ROR2 is evolutionarily conserved (Katoh and Katoh, 2005); ROR2 and the related ROR1 have an amino acid homology of 58 %. For Drosophila melanogster counterparts see: Dror, Dnrk.
Oishi et al (2003) and Mikels and Nusse (2006) have reported that ROR2 is a receptor for Wnt-5a and participates in inhibiting
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