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RHAMM

[receptor for hyaluronic acid-mediated motility; Receptor for HA-Mediated Motility] The approved gene symbol is HMMR [hyaluran-mediated motility receptor].

RHAMM has been identified as one of the cell surface receptors for hyaluronan by Hardwick et al (1992). Entwiste et al (1995) have characterized the murine gene.

Hyaluronan is a ubiquitous component of the extracellular matrix that also occurs transiently in the nucleus and cytoplasm. It mediates promotion of cell motility, adhesion, and proliferation by interacting with one of its receptors (CD44, RHAMM, and ICAM-1 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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