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RDP

[rabies virus glycoprotein derived peptide] This peptide, KSVRTWNEIIPSKGCLRVGGRCHPHVNGGGRRRRRRRRR, derived from rabies virus glycoprotein, a protein involved in mediating virus entry into host cells, corresponds to RDP(330-357) [rabies virus glycoprotein(330-357)] The peptide has been shown to deliver several proteins and DNA into the mouse brain, including BDNF, GDNF, plasmids, and the BDNF gene (Fu et al, 2012).

RDP cellular uptake is thought to involve a GABA receptor-dependent, clathrin-mediated endocytosis pathway (Fu et al, 2013). A conjugate of RDP and GDNF ... ... ... ... ... Subscribe to continue reading! ... ...

 

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