RCOR1

[REST corepressor 1] This protein is being referred to also as RCOR [REST corepressor]. The gene has been identified independently as KIAA0071.

Andrés et al (1999) have identified the protein as CoREST [corepressor for element-1-silencing transcription factor] showing that it functions as a corepressor of REST [RE1 silencing transcription factor] (NRSF [neural-restrictive silencing factor], a protein that is responsible, at least in part, for long-term repression in non-neural cells of genes encoding proteins critical to the neuronal phenotype (Lunyak et al, 2002).

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Entry last modified: August 2014