RAMP2

(approved gene symbol) [receptor activity-modifying protein-2]. In databanks the terms CRLR activity-modifying protein 2 [Calcitonin-receptor-like receptor activity-modifying protein 2] are given als alternative designations. The human RAMP3 gene maps to chromosome 17q21.2 (Derst et al, 2000).

This type 1 transmembrane protein has been identified by searching EST databases for sequences related to RAMP1 (McLatchie et al, 1998). RAMP2 transcripts have been found in the lung, breast, immune system tissues, and fetal tissues. Coexpression of RAMP2 and the calcitonin gene-related peptide receptor results in the formation of a functional receptor for adrenomedullin ... ... ... ...
 
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Entry last modified: January 2003