RAMP2
(approved gene symbol) [receptor activity-modifying protein-2]. In databanks the terms CRLR activity-modifying protein 2 [Calcitonin-receptor-like receptor activity-modifying protein 2] are given als alternative designations.
This type 1 transmembrane protein has been identified by searching EST databases for sequences related to RAMP1 (McLatchie et al, 1998). RAMP2 transcripts have been found in the lung, breast, immune system tissues, and fetal tissues. Coexpression of RAMP2 and the calcitonin gene-related peptide receptor results in the formation of a functional receptor for adrenomedullin. This receptor does not respond to calcitonin gene-related peptide, calcitonin, or
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