PYD |
PYDC2 |
tax-transcriptionally activated glycoprotein 1 ligand |
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[pyrin domain-containing 1] This is the approved gene symbol for a protein described originally as POP-1 [pyrin-only protein 1] (Bertin), which has been renamed ASC2 [apoptosis-associated speck-like protein containing a CARD2]. The human protein contains a pyrin domain and has been identified as a modulator of NF-kappa-B activation and caspase-1 activation through its interaction with the pyrin domain of ASC (CARD12) (Stehlik et al, 2003).
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