PVNZ112.3-CBP |
Pvr |
L8C |
||
[Parapoxvirus of red deer in New Zealand chemokine binding protein ORF112.6; ORF112.6 chemokine binding protein] This virus-encoded chemokine binding protein has been identified by Sharif et al (2019) in Parapoxvirus of red deer in New Zealand (PVNZ), a species of the Parapoxvirus genus that causes pustular dermatitis.
The protein binds CXCL4, CXCL10, CCL2, CCL3, CCL5, CCL19, CCL21, CCL22 and is thought to play a role in suppressing inflammation and the anti-viral immune response. Chemotaxis assays using neutrophils and monocytes shows that the
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