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OX44

OX44 (also: MOX44, for MRC OX44) is a monoclonal antibody that labels all myeloid cells and peripheral lymphoid cells but only 12 % of thymocytes in the rat (Paterson et al, 1987). Thymic cells expressing the corresponding antigen include most if not all cells found in the medulla but only a small fraction of the cortical cells. Most CD4(-) CD8(-) cells express OX44, whereas almost all CD4(+) CD8(+) cells do not express the antigen. In functional tests, the cells expressing OX44 account for all proliferation by thymocytes when stimulated by allogeneic spleen ... ... ... ... ... Subscribe to continue reading! ... ...

 

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