OM-LV20

This peptide with the sequence LVGKLLKGAVGDVCGLLPIC has been isolated from skin secretions of the odorous frog Odorrana margaretae. The peptide contains an intramolecular disulfide bridge at the C-terminus, and is produced by post-translational processing of a 71-residue prepropeptide. OM-LV20 is not an antimicrobial peptide, has no hemolytic activity, or acute toxicity, but exhibits weak antioxidant activity. OM-LV20 promotes wound healing against human keratinocytes (HaCaT) and human skin fibroblasts. It induces proliferation of HaCaT but skin fibroblast cells. OM-LV20 strongly promotes wound healing ... ... ... ...
 
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Entry last modified: December 2018