OB-fold |
obl |
LD78 receptor |
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[osteoblastogenesis inhibitory factor] This factor has been isolated from the conditioned medium of mouse osteoclast-like myeloma cell line RAW264.7 treated with RANKL (Kubota et al, 2002). The factor inhibits the differentiation of mouse osteoblast precursor-like cell line MC3T3-E1 to osteoblasts induced by BMP4. Kubota et al (2002) have identified OBIF as the homodimeric form of PDGF, PDGF-BB.
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