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OA-GL21

This peptide with the sequence GLLSGHYGRVVSTQSGHYGRG from the skin secretions of the frog Odorrana andersonii (Bian et al, 2018). OA-GL21 promotes wound healing of human keratinocytes (HaCaT) and human fibroblasts but does not significantly affect their proliferation. OA-GL21 promotes wound healing in a full-thickness skin wound model in dose- and scar-free manners. The peptide has no direct antibacterial, hemolytic, and acute toxic activity. It has weak antioxidant activities and is highly stable.

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