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Nischarin

approved gene symbol: NISCH. The human homolog of Nischarin has been identified as IRAS [Imidazoline Receptor Antisera-Selected] and has been implicated in protection of cells against cell death by apoptosis. The cDNA has been identified independently as KIAA0975.


The murine Nischarin murine protein has been identified by Alahari et al (2000). The cytosolic protein binds preferentially to the cytoplasmic domain of the integrin-alpha-5 subunit of the fibronectin receptor, inhibits cell motility, and alters actin ... ... ... ... ... Subscribe to continue reading! ... ...

 

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