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NLRX1

[NLR family member X1] This is the approved gene symbol for a protein identified independently as CLR11.3, a member of the CLR family (see also: NLR family). It is known also NOD9 [Nucleotide-binding oligomerization domain protein 9] (Ting et al, 2008; Inohara et al, 2005).

NLRX1 is expressed ubiquitously in human tissues, with the strongest expression observed in mammary gland, heart and muscle and is expressed constitutively in several human cell lines (HeLa cells, HEK293T, MCF-7 breast cancer cells, Ramos, Jurkat, THP1 monocytes) (Tattoli et al, 2008).

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