NLRP6 inflammasome |
NLRP8 |
iPS cells |
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[NLR family, pyrin-domain containing 7] This is the approved gene symbol for proteins that have been described as PYPAF3 [Pyrin-containing APAF-1-like protein 3], NOD12 [Nucleotide-binding oligomerization domain protein 12], and NALP7 [NACHT-LRR-PYD-containing protein-7]. A databank alias is PAN7 [PAAD and NACHT-containing protein 7]. The proteins are members of a group of related proteins implicated in the activation of pro-inflammatory caspases involving the inflammasome multiprotein complex (Tschopp et al, 2003). NLRP7 is a member of the CLR family (NLR family
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