NLIKQDDGGSPIRHY |
NLKAIAALAKKLL |
FNIII14 peptide |
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[neuroleukin] This factor of 56 kDa was purified initially from mouse salivary gland (Gurney et al, 1986). It is produced also by T-cells stimulated with lectins. Some glioma cell lines produce NLK constitutively (Spear and Gurney, 1988). The factor is secreted also by Gc 4 PF murine fibrosarcoma cells (Watanabe et al, 1996) and has been identified independently as myeloid leukemia cell differentiation factor.
Neuroleukin has been shown to be identical with the autocrine motility factor (see: AMF), a tumor-secreted cytokine
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