NGF-2

[Nerve growth factor-2] A cDNA encoding nerve growth factor-2 has been cloned from a human glioma cDNA library (Kaisho et al, 1990). The cloned cDNA encodes a polypeptide of 257 amino acids including a preproprotein sequence of 138 residues and a mature region of 119 residues.

The amino acid sequence of human NGF-2 exhibits 58 % similarity with that of human NGF. A 1.5 kb of NGF-2 mRNA can be detected from an early development stage in rat brain.

Conditioned medium of COS-7 cells expressing human NGF-2 cDNA ... ... ... ...
 
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