MPC |
MPCA inducing factor |
BCL2-beta |
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An established mouse plasmacytoma cell line that produces IgG2b. The cells have been used to study the rearrangement of immunoglobulin genes and for addressing a number of cell biological questions.
Phillips et al (1999) have used these cells in bioassays for human Activin A and human Activin B, which inhibit proliferation of these cells. Inhibins, follistatin, and TGF-beta-1, TGF-beta-2, and TGF-beta-3 have no effect. Follistatin blocks the inhibitory effect of Activin A.
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