MMP-15

[matrix metalloproteinase-15] According to a numerical nomenclature for matrix metalloproteinases this is the new name for MT2-MMP [Membrane-type matrix metalloproteinase-2] Also: MT-MMP-2.

The human gene maps to chromosome 16q12.2-q21 (Sato et al, 1997). The gene has been cloned from a human lung and placenta cDNA library (Takino et al, 1995; Will and Hinzmann et al, 1995) and mouse lung (Tanaka et al, 1997). The protein has been shown to be located on the cell membrane.

Bar-Or et al (2003) have observed high expression of MMP-15 in T-cells ... ... ... ...
 
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Entry last modified: March 2006