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LyD9

A murine Ly1(+), Mac-1(+), B220(+), CD11(+) precursor B-cell line that depends on IL3 for its growth and is used in bioassays for this factor. The cells die by apoptosis in response to growth factor deprivation. The cells have been shown to grow in response to a combination of TNF-alpha and IL2, although neither factor alone can stimulate proliferation.

DNA synthesis but not actual growth of LyD9 cells is stimulated to some extent by IL7. Antibodies against IL4 and IL6 ... ... ... ... ... Subscribe to continue reading! ... ...

 

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