LvIAP1

[Litopenaeus vannamei inhibitor of apoptosis 1] This inhibitor of apoptosis from the Pacific white shrimp Litopenaeus vannamei contains three BIR domains and one RING domain and is an ortholog of PmIAP [Penaeus monodon inhibitor of apoptosis protein]. The protein is expressed highly in almost all tissues and is essential for shrimp survival. Silencing of LvIAP1 expression causes death of the shrimp within 48h after injection of the corresponding dsRNA. For a related protein see also: LvIAP2 [Litopenaeus vannamei inhibitor of apoptosis 2]. In LvIAP1-silenced shrimps, the number of circulating hemocytes decreases dramatically because of extensive cell death by apoptosis ... ... ... ...
 
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Entry last modified: December 2012