Liver sinusoidal endothelial cells

abbr. LSECs, SECs, HSECs [hepatic sinusoidal endothelial cells]. Liver sinusoidal endothelial cells comprise approximately 50 % of the non-parenchymal hepatic cells. They separate hepatocytes from the passing blood and play an important role in hepatic microcirculation (Oda et al, 2003). These cells lack a basement membrane, form a fenestrated monolayer (Braet and Wiese, 2002), express a variety of scavenger receptors, and control the exchange of material between the blood and the liver parenchyma, constituting the most powerful scavenger system in the body (Enomoto et al, 2004; Smedsrod et al, 1990). Liver sinusoidal endothelial cells function as a scavenger ... ... ... ...
 
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Entry last modified: May 2022