Laminin-alpha-1(2747-2765) |
Laminin-alpha-3(1476-1487) |
hugin-PK |
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[LAMA3(1411-1422)] This fragment of human laminin-alpha-3 with the sequence KNSFMALYLSKG is being referred to also as A3G75 peptide. The peptide binds to syndecan-2 and syndecan-4 and promotes cell attachment and neurite outgrowth in PC12 rat pheochromocytoma cells (Kato et al, 2002). If generated in vivo, for example, by proteolytic cleavage by matrix metalloproteinases, this fragment or a fragment containing this sequence might act as a matrikine.
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