LTV peptide |
Ltxs1 |
oligosaccharyltransferase 2 homolog |
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This peptide, sometimes referred to as LTV peptide, has been identified by Shadidi and Sioud (2003) phage display selection as a tumor-targeting peptide that exhibit specific binding to breast cancer cells. The peptide does not bind to human primary cells from different tissue origin (e.g., epithelial cells, endothelial cells, hematopoetic cells). The peptide can function as a cell-penetrating peptide. A construct consisting of LTVSPWY peptide fused to an antisense phosphorothioate oligonucleotide against the ErbB2
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