KREMEN2 |
KRFGRLAKSFLRMRILLPRRKILLAS |
Krüppel-like factor 4 |
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KRF17 is a peptide (KRFKQDGGWSHWSPWSS) derived from the heparin-binding region of thrombospondin-1. This peptide has antimicrobial activities against the Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa and is active also against the Gram-positive Bacillus subtilis. The peptide is not hemolytic for erythrocytes and does not have membrane permeabilising effects on human epithelial cells (Malmstren et al, 2006).
For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.
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