Intelectin-2

abbr. ITLN2. Intelectin-2 shows 91 % sequence homology with Intelectin (Pemberton et al, 2004). Lee et al (2001) have called Intelectin-2 as HL-2 [Endothelial lectin HL-2]) and identified it as the human homolog of Xenopus oocyte lectin XL-35).

The Intelectin-2 gene is absent from the C57BL/10 genome but present in the genome of BALB/c mice. The protein is expressed by intestinal goblet cells, and its expression is upregulated after infection with the nematode parasite Trichinella spiralis. BALB/c mice, which express Intelectin-2 are resistant to this nematode, whereas C57BL/10 ... ... ... ...
 
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Entry last modified: June 2008