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IRF7

(approved gene symbol) [interferon regulatory factor-7] The sequence for IRF7 was obtained by Zhang and Pagano (1997) using a yeast 1-hybrid system with an EBV protein-binding sequence as bait. Several truncated splice variants are known. The protein contains a domain called SMIR (SMAD-IRF-binding domain) found also in IRF3 and IRF6.

The protein encoded by IRF7 is being referred to also as IRF7A [interferon regulatory factor-7A], encoding a protein of 69 kDa (503 amino acids). IRF7B [interferon regulatory factor-7B] (67 kDa) is a variant that lacks 29 amino acids present in IRF7A ... ... ... ... ... Subscribe to continue reading! ... ...

 

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