IL33 |
IL33 receptor |
terminally differentiated EM cells |
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[IL33 receptor]. Schmitz et al (2005) have shown that IL33 binds and signals through a protein described variously as T1, ST2 (ST2L), T1/ST2, Fit-1 [fos-induced transcript-1]. The receptor is identical with IL1RL1 [IL1 receptor-like-1], and, being a member of the IL1 receptor family, is referred to also as IL1R4. The receptor is known also as DER4 [delayed early response gene 4].
Xu et al (2008) have reported that knock-out mice lacking expression of IL33R show an attenuated induction of collagen-induced arthritis, as well as reduced production of
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