IL2 |
IL2 enhancing factor |
lifeguard 4 |
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This protein has been identified by Eitan et al (1992) as a factor produced by regenerating optic nerves from fish that is cytotoxic to oligodendrocytes. Eitan et al (1993) have reported that a nerve transglutaminase purified from regenerating optic nerves of fish catalyzes the dimerization of human IL2. The dimerized IL2, unlike monomeric IL2, is cytotoxic to oligodendrocytes from rat brain in culture.
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