IL17RC(376-387) |
IL17RE |
fibrinogen-gamma-57.5 |
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[interleukin-17 receptor D; IL17 receptor D] IL17RD (approved gene symbol) is a homolog of zebrafish SEF (an acronym of similar expression to FGF). Zebrafish SEF encodes a conserved putative transmembrane protein that shares sequence similarities with the intracellular domain of the IL17 receptor. SEF functions as a feedback-induced antagonist of Ras/Raf/MEK/MAPK-mediated fibroblast growth factor signaling. It interacts with FGFR1 and FGFR2 and modulates receptor activity (Tsang et al, 2002; Furthauer et al, 2002).
The gene encoding the human
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