IGFBP6b |
IGFBP8 |
Myeloblastin |
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[Insulin-like growth factor binding protein-7] This name has been proposed by Oh et al (1996) as a designation for a protein encoded by a cDNA termed mac25 identified originally by Murphy et al (1993). Oh et al (1996) have cloned the mac25 cDNA from Hs578T mammary carcinoma cells and have shown that the mature protein binds both IGF-1 and IGF-2. IGFBP-7 exhibits low affinity for IGF-1, but has a relatively high affinity for insulin and blocks insulin binding to the insulin receptor
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