IGF-3

[Insulin-like growth factor-3] This protein (72 amino acids), which has been identified in Xenopus laevis, is related to mammalian IGF-1 and IGF-2 and belong to the IGF family. IGF-3 is expressed in the dorsal midline during gastrulation and neurulation in a pattern overlapping with IGFBP5. IGF-3 is expressed strongly in the prospective ventral forebrain region of the anterior neural plate and participates in neural and head induction (Pera et al, 2001).

Wang et al (2008) have identified IGF-3 in teleost fish (zebrafish and tilapia). The expression of IGF-3 is gonad-specific and starts early in fish development. IGF-3 is expressed in the ... ... ... ...
 
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Entry last modified: February 2019