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HTK

[HTK(+), HTK(-)]

[hepatoma transmembrane kinase] HTK (987 amino acids) was identified initially as a novel transmembrane protein tyrosine kinase in human bone marrow cells expressing the cell surface marker CD34, and in the human hepatocellular carcinoma cell line, Hep3B (Bennett et al, 1994. HTK belongs to the EPH subfamily of tyrosine kinases and is identical with EphB4 (see: ephrins). The human gene maps to chromosome 7. HTK and murine myk1 are homologous.

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