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Galectin-12

The approved gene symbol is LGALS12 [lectin galactoside-binding soluble 12; Galactoside-binding soluble lectin 12]. In databanks the protein is known also as GRIP1 [Galectin-related inhibitor of proliferation].

The gene encoding galectin-12 has been cloned by Yang et al (2001). The protein contains carbohydrate recognition domain and binds lactose. Galectin-12 mRNA is expressed sparingly or undetectable in many tissues, but it is up-regulated in cells synchronized at the G1 phase or the G1/S boundary of the cell cycle. Ectopic expression of galectin-12 in cancer cells causes cell cycle arrest at the ... ... ... ... ... Subscribe to continue reading! ... ...

 

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