GSDMC |
GSDMDC1 |
KIAA0317 |
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(approved gene symbol) [gasdermin D] GSDMD is a member of the family of gasdermins. The gene has been identified by Katoh and Katoh, who referred to it as DFNA5L or DF5L [DFNA5-like], owing to sequence homology with DFNA5, which is the same as GSDME [gasdermin E]. In databanks orthologs of the protein in other species are known also as GSDMDC1 [Gasdermin domain-containing protein 1].
GSDMD is expressed in a highly tissue-specific manner in the epithelium of skin and the gastrointestinal tract, but the phenotype of GSDMD knock-out mice
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