GRLYSFGLamide |
GRMP |
J774 |
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[Glucosteroid response-modifying factor] This biochemically uncharacterized factor is produced by mouse spleen cells and a murine T-cell hybridoma, FS6 14.13.1 after stimulation with concanavalin A (Fairchild et al, 1984). GRMFT blocks glucosteroid suppression of T-helper cell functions and the growth of progenitor cells of granulocytes and macrophages in vitro (see also: hematopoiesis, hematopoietic stem cells).
GRMFT does not appear to be identical with IL1, IL2, IL3, IFN-gamma. The factor is probably not identical with various
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