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FGF21

(approved gene symbol) [Fibroblast growth factor-21] This protein is a secreted member of the fibroblast growth factor (FGF) family of proteins and has been isolated from mouse embryos. FGF21 mRNA is most abundant in the liver. Lower levels are observed in the thymus. Human and murine FGF21 show approximately 75 % amino acid identity. FGF21 is most similar (approximately 35 % amino acid identity) to human FGF19 (Nishimura et al, 2000).

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