Eotaxin

This protein of 73 amino acids has been found in the bronchoalveolar lavage of guinea pigs used as a model of allergic inflammation. The factor belongs to the platelet factor-4 family (see: PF4) of Chemokines. It exhibits homology of 53 % with human MCP-1, 44 % with guinea pig MCP-1, 31 % with human MIP-1-alpha, and 26 % with human RANTES. Eotaxin is 60 % identical with MCP-4 (Monocyte chemotactic protein-4). The factor is known also as SCYA11. The factor is being referred to also as Eotaxin-1 (following the identification of related factors ... ... ... ...
 
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Entry last modified: January 2002