Endokinins

The four endokinins are members of the family of neuropeptides termed tachykinins. They are encoded by a single gene TAC4 [tachykinin precursor 4; tachykinin-4] gene, which is expressed primarily in the adrenal gland and in the placenta.

Endokinin A (abbr. EKA; DGGEEQTLSTEAETWVIVALEEGAGPSIQLQLQEVKTGKASQFFGLM) corresponds to human TAC4(21-67)

Endokinin B (abbr. EKB; DGGEEQTLSTEAETWEGAGPSIQLQLQEVKGKASQFFGLM). Endokinin B differs from Endokinin A by a short internal deletion of six amino acids.

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Entry last modified: February 2011