ETF
[EGFR-specific transcription factor] A transcription factor of 120 kDa identified originally by its ability to specifically stimulate expression of EGF receptors.
A binding site for ETF has been identified also in the promoter region of the gene encoding the receptor for IGF-1 (see: IGF) and in the RET gene promoter. ETF recognizes various GC-rich sequences in the promoter regions of various other genes and appears to be a specific transcription factor for promoters that do not contain TATA box elements (see also: gene expression).
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