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EMR2

[EGF-like module containing mucin-like hormone receptor-like-2] The approved gene symbol is ADGRE2 [Adhesion G protein-coupled receptor E2].

Lin et al (2000) have identified EMR2, a member of the EGF-TM7 family of G-protein-coupled receptors. The molecular characteristics of EMR2 are strikingly similar to thosse of CD97. EMR2 contains five tandem EGF-like domains and expresses similar protein isoforms consisting of various numbers of EGF-like domains as a result of alternative RNA splicing. EMR2 and CD97 also exhibit highly homologous EGF-like domains and share identical gene organization. EMR2 expression appears to be restricted to monocytes, ... ... ... ... ... Subscribe to continue reading! ... ...

 

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