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ECSM2

[endothelial cell-specific chemotaxis regulator] This protein has been described independently as ARIA [apoptosis regulator through modulating IAP expression] and ECSCR [endothelial cell-specific chemotaxis regulator] (approved gene symbol). It plays a role in cell death by apoptosis and the regulation of angiogenesis.

The cDNA encoding ECSM2 (205 amino acid transmembrane protein) has been cloned by Armstrong et al (2008). ECSM2 is expressed exclusively in the plasma membrane of endothelial cells. Knock-down of ECSM2 expression in human umbilical vein endothelial cells reduces ... ... ... ... ... Subscribe to continue reading! ... ...

 

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