DNA editing deaminases |
DN B-cells |
demilune cell and parotid protein gene 1 |
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[hypomethylation, hypomethylated, hypermethylation, hypermethylated]
see: gene expression.
The term DNA methylation refers to the addition of a methyl group to the carbon 5 of cytosine, which yields 5-Methyl-Cytosine. The transfer of the methyl group from S-adenyl methionine to the cytosine residue is catalyzed by a family of DNA methyltransferases, some of which establish a new methylation pattern to unmodified DNA, while others copy the DNA methylation pattern of a DNA during DNA replication. DNA methylation mostly occurs in cytosine residues that precede a guanine nucleotide (CpG dinucleotide) and can occur in intergenic regions, within a gene, or in the promoter of a gene. So-called CpG Islands, which comprise stretches of DNA
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