DDX36 |
DDX58 |
Mdeiger |
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[DEAD box polypeptide 41; DEAD box protein 41] This human gene is thought to be the ortholog of Drosophila melanogaster abstrakt gene (gene: CG14637) (Irion and Leptin, 1999). The protein belongs to a large family of RNA helicases containing a DEAD box and is being referred to also as DEAD box helicase 41.
DDX41 has been shown to be involved in innate immune responses. Zhang et al (2011) have identified DDX41 as an intracellular DNA sensor and pattern recognition receptor in myeloid dendritic cells. Knock-down of DDX41 expression blocks the ability of these
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