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DCAF12

[DDB1 and CUL4 associated factor 12] This gene has been identified independently as KIAA1892 (Nagase et al, 2001). In databanks the gene is known also as WDR40A [WD repeat domain 40A]. Li S et al (2008) have identified the protein as a centrosome protein termed TCC52, stating that the gene is highly expressed in prostate cancer, cholangiocarcinoma, laryngeal cancer, and lung cancer, and some cancer cell lines. A databank synonym is CT102 [cancer/testis antigen 102].

It is thought that the protein is involved in the pathway protein ubiquitination (Angers et al, 2006; Jin et al, 2006).


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