Cellular cannibalism

This term was used originally to describe as a large cell enclosing a slightly smaller one within its cytoplasm (Sharma and Dey, 2011). These authors have stated that cannibalism is completely different from phagocytosis, entosis, and emperipolesis (for overview see also: Yang and Li, 2012) and can be used as a morphological criterium to distinguish benign from malignant lesions. Cannibalism has been described in various cancers such as, bladder cancer, breast cancer, lung cancer, etc, and this is related with the aggressiveness of the malignancy.

The term cellular cannibalism has been used to describe a process observed with metastatic tumor cells under starvation. Such cells can actively engulf live or dead cells by a mechanism similar to phagocytosis. Cannibalism is more or less non-selective and can involve engulfment of ... ... ... ...
 
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Entry last modified: AUGUST 2018