CREM

[CRE Modulator; cAMP Response Element Modulator; cAMP responsive element modulator]; abbr. in some publications also CREM/ICER or ICER/CREM.

CREM is a transcription factor that has been identified by Foulkes NS et al (1991) as a gene encoding a protein that is highly homologous to the DNA-binding protein CREB, a factor regulating cAMP second messenger pathways through binding to response elements known as CRE [Cyclic AMP-responsive element], which are present in the promoters of many viral and cellular genes. The authors have reported that, like CREB ... ... ... ...
 
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Entry last modified: March 2024