CR1
In the nomenclature of CD antigens this protein has been given the designation CD35.
Humans and other primates have a distinct CR1 gene, whereas the mouse differs in that a single mouse CR2 gene encodes both CR1 and CR2, with CR1 being generated via alternative splicing while primates utilize distinct genes for the CR1 and CR2 proteins (for overview see: Jacobson AC, Weis, 2008). The mouse proteins may be expressed differentially. For example, Donius et al (2013) have reported that CR1 is the dominant isoform in mouse follicular dendritic cells , whereas CR2 is expressed preferentially by mouse
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