CNTF

[Ciliary neuronotrophic factor; ciliary neurotrophic factor]

ALTERNATIVE NAMES

MANS (membrane-associated neurotransmitter stimulating factor).

SOURCES

CNTF is found predominantly in peripheral nerve tissues. The main source appears to be myelin-associated Schwann cells in peripheral nerves and astrocytes in the central nervous system. CNTF is present at very high concentrations within intraocular tissues that contain the same muscle cells innervated by ciliary ganglionic neurons in vivo. A substantial portion of the cholinergic differentiation and ciliary neurotrophic activities present in MANS ( ... ... ... ...
 
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Entry last modified: April 2000