CD312

Other designations:

EMR2 [EGF-like module containing mucin-like hormone receptor-like-2]. The approved gene symbol is ADGRE2 [Adhesion G-protein-coupled receptor E2].

The cDNA encoding EMR2 has been identified by Lin et al (2000). EMR2 is a protein of 823 amino acids and has multiple splice variants. Chiu et al (2008) have reported that EMR2 in human leukocytes can undergo trans-splicing. This gives rise to a chimeric molecule that contains the EGF-like motif 3 of CD97 and is functional in ligand binding like the parent molecules and may be a strategy employed by leukocytes ... ... ... ...
 
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Entry last modified: August 2010