CARD12 |
CARD15 |
ILC22 |
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[caspase recruitment domain-containing protein-14] CARD14 (Bertin et al, 2001) contains an N-terminal caspase recruitment domain (CARD). It also contains a C-terminal PDZ domain, an SH3 domain, and a GUK domain. CARD14 participates in signaling cell death by apoptosis by activating transcription factor NF-kappa-B and by binding to BCL10. The protein has been described as CARMA2 [CARD-MAGUK protein-2] by Gaide et al (2002) and is known also as BIMP2 [BCL10-interacting MAGUK protein 2] (McAllister-Lucas et al, 2001).
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